If I understand this all correctly, the major implication here is that if Soyuz can not be cleared for a return to flight before the end of December (and they’re just beginning the investigation into what went wrong) there is a high likelihood that the space station will be flying uncrewed.

https://www.theverge.com/2018/10/11/17963872/nasa-international-space-station-soyuz-launch-failure

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